Potassium form, oo ah cunto-ku-darka quudinta aan antibiyootiga ahayn ee ugu horreysay oo ay ansixisay Midowga Yurub sannadkii 2001 oo ay ansixisay Wasaaradda Beeraha Shiinaha sannadkii 2005, ayaa ururisay qorshe codsi oo bisil in ka badan 10 sano, waraaqo cilmi-baaris oo badan oo gudaha iyo dibaddaba ah ayaa ka warbixiyay saamaynta ay ku leedahay marxaladaha kala duwan ee koritaanka doofaarka.

Cudurka Necrotizing enteritis waa cudur digaag oo caalami ah oo ay keento bakteeriyada gram-positive (Clostridium perfringens), kaas oo kordhin doona dhimashada digaagga digaagga isla markaana yareyn doona waxqabadka koritaanka digaagga si aan caafimaad ahayn. Labadan natiijo waxay waxyeeleeyaan daryeelka xayawaanka waxayna keenaan khasaare dhaqaale oo weyn oo soo saarista digaagga ah. Wax soo saarka dhabta ah, antibiyootikada ayaa badanaa lagu daraa quudinta si looga hortago dhacdada cudurka necrotizing enteritis. Si kastaba ha ahaatee, baaqa ah in la mamnuuco antibiyootikada quudinta ayaa sii kordhaya, waxaana loo baahan yahay xalal kale si loo beddelo saameynta ka hortagga antibiyootikada. Daraasaddu waxay ogaatay in ku darista asiidhyada dabiiciga ah ama milixdooda cuntada ay joojin karto waxa ku jira Clostridium perfringens, taasoo yaraynaysa dhacdada cudurka necrotizing enteritis. Potassium formate waxaa loo kala saaraa asiidh formic iyo potassium formate xiidmaha. Sababtoo ah hantida isku xidhka covalent ee heerkulka, qaar ka mid ah asiidh formic ah ayaa si buuxda u gala xiidmaha. Tijaabadan waxay isticmaashay digaagga qaba cudurka necrotizing enteritis qaab cilmi baaris ah si loo baaro saameyntaqaabka potassium-kawaxqabadka koritaankiisa, microbiota xiidmaha, iyo maadada aashitada dufanka leh ee silsiladda gaaban.

1. SaamayntaBotashiyam kala duwanku saabsan Waxqabadka Kobaca ee Broilers-ka qaba Cudurka Necrotizing Enteritis.

Natiijooyinka tijaabada ah waxay muujiyeen in fosfateam formate uusan saameyn weyn ku lahayn waxqabadka koritaanka ee broilers-ka leh ama aan lahayn caabuqa enteritis-ka ee necrotizing ama aan lahayn, taas oo la jaanqaadaysa natiijooyinka cilmi-baarista ee Hernandez et al. (2006). Waxaa la ogaaday in isla qiyaasta kaalshiyamka formate uusan saameyn weyn ku lahayn korodhka miisaanka maalinlaha ah iyo saamiga quudinta ee broilers-ka, laakiin markii ku darista kaalshiyamka formate ay gaartay 15 g/kg, waxay si weyn u yareysay waxqabadka koritaanka ee broilers-ka (Patten iyo Waldroup, 1988). Si kastaba ha ahaatee, Selle et al. (2004) waxay ogaadeen in ku darista 6 g/kg oo posfateam formate cuntada ay si weyn u kordhisay kordhinta miisaanka iyo qaadashada quudinta digaagga broiler 16-35 maalmood. Hadda waxaa jira warbixino cilmi-baaris oo yar oo ku saabsan doorka asiidhyada dabiiciga ah ee ka hortagga caabuqa enteritis-ka ee necrotizing. Tijaabadani waxay ogaatay in ku darista 4 g/kg oo posfateam formate cuntada ay si weyn u yareysay heerka dhimashada ee broilers-ka, laakiin ma jirin xiriir saameyn-qiyaas ah oo u dhexeeya dhimista heerka dhimashada iyo xaddiga posfateam ee lagu daray.

2. SaamayntaBotashiyam kala duwanku saabsan Waxyaabaha Microbial-ka ah ee ku jira unugyada iyo xubnaha digaagga ee qaba cudurka Necrotizing Enteritis

Ku darista 45mg/kg bacitracin zinc ee quudinta ayaa yareysay dhimashada broilers-ka qaba cudurka necrotizing enteritis, isla markaana waxay yareysay tirada Clostridium perfringens ee jejunum, taasoo la jaanqaadaysay natiijooyinka cilmi-baarista ee Kocher et al. (2004). Ma jirin saameyn muhiim ah oo ku saabsan kaabista potassium diformate ee cuntada ee ku jirta Clostridium perfringens ee jejunum ee broilers-ka qaba cudurka necrotizing enteritis muddo 15 maalmood ah. Walsh et al. (2004) waxay ogaadeen in cuntooyinka aashitada sare leh ay saameyn xun ku leeyihiin aashitada dabiiciga ah, sidaa darteed, aashitada sare ee cuntooyinka borotiinka sare leh waxay yareyn kartaa saameynta ka hortagga ah ee potassium formate ee necrotizing enteritis. Tijaabadani waxay sidoo kale ogaatay in potassium formate ay kordhisay tirada lactobacilli ee caloosha muruqa ee digaagga broiler-ka ee 35d, taas oo aan waafaqsanayn Knarreborg et al. (2002) oo lagu ogaaday in vitro in potassium formate ay yareysay koritaanka lactobacilli ee caloosha doofaarka.

3.Saamaynta potassium 3-dimethylformate ee pH-ga unugyada iyo heerka aashitada dufanka leh ee silsiladda gaaban ee digaagga broiler-ka ah ee qaba cudurka necrotizing enteritis

Saamaynta bakteeriyada dila ee asiidhyada dabiiciga ah ayaa la rumeysan yahay inay inta badan ka dhacdo qaybta sare ee habka dheefshiidka. Natiijooyinka tijaabadan waxay muujiyeen in potassium dicarboxylate ay kordhisay maadada formic acid ee duodenum 15 maalmood iyo jejunum 35 maalmood. Mroz (2005) wuxuu ogaaday in ay jiraan arrimo badan oo saameeya ficilka asiidhyada dabiiciga ah, sida pH quudinta, buffering/acidity, iyo dheelitirka elektrolytka cuntada. Aashitada oo hooseysa iyo qiimaha dheelitirka elektrolytka oo sarreeya ee cuntada ayaa kor u qaadi kara kala-goynta potassium form acid iyo potassium form. Sidaa darteed, heer ku habboon oo ah aashitada iyo qiimaha dheelitirka elektrolytka ee cuntada ayaa kor u qaadi kara horumarinta waxqabadka koritaanka ee broilers by potassium formate iyo saameynteeda ka hortagga ah ee necrotizing enteritis.

Gunaanad

Natiijooyinkaqaabka potassium-kaQaabka cudurka 'necrotizing enteritis' ee digaagga broiler ayaa muujiyay in potassium formate uu yareyn karo hoos u dhaca waxqabadka koritaanka digaagga broiler xaalado gaar ah iyadoo la kordhinayo miisaanka jirka iyo dhimista dhimashada, waxaana loo isticmaali karaa sidii wax lagu daro quudinta si loo xakameeyo caabuqa cudurka 'necrotizing enteritis' ee digaagga broiler.