1. Physicochemical Properties
Benzoic acid(benzenecarboxylic acid) waa aashitada udgoonka ugu fudud oo leh aysiidh daciif ah (kala-bax joogto ah 4.20). Wax yar bay ku milmi kartaa biyaha laakiin waxay si diyaar ah ugu milmi kartaa dareerayaasha organic sida ethanol. Sababtoo ah lipofilicity xooggan, waxay geli kartaa xuubabka unugyada microbial waxayna sameyn kartaa saameyn lid ku ah bakteeriyada iyadoo la joojinayo qaadashada amino acid, carqaladeyneysa dhaqdhaqaaqa enzyme neefta, iyo ka hortagga falcelinta uumiga acetyl-CoA.
2.Antimicrobial SpectrumWax ku ool u leh bakteeriyada, caaryada, iyo khamiirka, oo leh saameyn gaar ah oo la xoojiyey ee ilaalinta deegaanka acidic (tusaale, marka loo beddelo cusbada benzoate).
3.Metabolism iyo Badbaadada
Xayawaanka, benzoic acid ayaa ugu horrayn metabolized beerka, iyadoo in ka badan 85% laga soo saaray kaadida sida hippuric acid.
Bini'aadamka iyo doofaarradu waxay soo bandhigaan dariiqooyin dheef-shiid kiimikaad oo isku mid ah, oo leh ku dhowaad dhammaystiran oo saxaro ah 24 saacadood gudahood, taas oo muujinaysa badbaadada sare.
II. Codsiyada gaarka ah ee ku jira Quudinta
Xeerarka iyo Heerarka Qiyaasta
EUTan iyo 2003, benzoic acid ayaa loo oggolaaday sidii aashitada quudinta doofaarka ee 0.5% ~ 1.0%.
Shiinaha: Loo taxay sidii pH nidaamiye iyo ilaalin labadabaBuugga wax-ka-kordhinta ee quudinta (2013), iyada oo aan lahayn xaddidaad cad cad laakiin tixraacaya heerarka cuntada ee 0.2 ~ 1.0 g/kg.
Hawlaha iyo waxtarka
Antibiyootiga AlternativeKa dib mamnuuciddii EU-da ee 2006 ee antibiyootiga, benzoic acid waxay noqotay beddelka muhiimka ah sababtoo ah sifooyinka antimicrobial ballaaran ee spectrum, gaar ahaan ka hortagga shubanka naaska ka dib (PWD) iyo kor u qaadida koritaanka doofaarka.
Waxqabadka KobacaDaraasaduhu waxay muujinayaan in lagu daro 0.5% benzoic acid ay wanaajiso qaadashada quudinta iyo korodhka miisaanka doofaarka naaska laga jaray.
Isbarbardhigga Waxyaalaha Kale
Marka la barbardhigo potassium diformate, benzoic acid waxaa si degdeg ah u nuugaya horudhaca waxayna u baahan tahay tignoolajiyada dahaarka si ay ugu dhaqmaan hindgut, halka potassium diformate ay si toos ah u bartilmaameedsato duodenum, oo bixisa waxtarka antimicrobial sare.
Waqtiga boostada: Meey-15-2025

